Treatment · PeptidesCompounded

Wolverine Stack

BPC-157 and TB-500 together: two complementary recovery peptides in one clinician-led program, with labs, follow-up and a published monthly price.

  • Studied for soft-tissue repair and recovery
  • Two peptides thought to work by complementary routes
  • Used to support a structured loading and recovery plan

Individual results vary. The pair has not yet been compared with either peptide alone in a published trial, so your clinician agrees clear goals with you and reviews them at follow-up.

Choose your plan
2 months$650
$325/mo
  • Live visit with a licensed clinician
  • If prescribed, medication is included in the price and delivered to your home
  • Subscription, cancel anytime

Indicative price · confirmed after eligibility · prescription treatment

Peptides Treatment
Peptides
What it is

What is in the Wolverine Stack

The Wolverine Stack is the peptide community's name for one of the most popular recovery pairings: BPC-157 and TB-500. We kept the name because it is what people search for. What we added is the clinical program around it.

BPC-157 is a synthetic peptide based on a sequence found in a protein in gastric juice, studied for soft-tissue repair and the gut lining. It has a page of its own.

TB-500 is a short synthetic peptide corresponding to an active region of thymosin beta-4, a naturally occurring protein involved in cell movement and the organization of actin. It is studied for the cell-migration and blood-supply side of repair. It is not the full thymosin beta-4 protein, so research on that protein does not automatically apply to it.

The appeal of pairing them is complementary mechanisms: one studied mainly for the rebuilding side of repair, one for cell movement and blood supply. Your clinician helps you decide whether the pair or a single peptide suits your goals.

The Wolverine Stack pairs BPC-157 with TB-500, a synthetic peptide fragment related to thymosin beta-4. Both are studied for their role in tissue repair, and they are thought to act by different routes, which is why people choose them together. Neither is FDA-approved; both are prepared by a licensed compounding pharmacy under an individual prescription, and neither is equivalent to or interchangeable with any branded medication.

Our model

How it works here

Every plan follows one path. Each step feeds the next. See the Peptide Therapy approach.

  1. 01

    Measure

    We baseline your labs, history, and goals.

  2. 02

    Plan

    A clinician decides whether this fits — and what else might serve you.

  3. 03

    Act

    If appropriate, you start with clear guidance and high-touch support.

  4. 04

    Track

    We monitor how you respond on a defined cadence.

  5. 05

    Adjust

    Protocols are refined over time. Guided care, not a kit in the mail.

Why people choose the Wolverine Stack

The stack is two well-known peptides prescribed together. Here is what each brings, and what you get as a pair.

Why people choose the Wolverine Stack
BPC-157TB-500The Wolverine Stack
What it isSynthetic peptide based on a gastric-juice sequenceSynthetic fragment related to thymosin beta-4Both, prescribed together in one program
Studied forSoft-tissue repair and the gut liningCell movement and blood supply in repairBoth sides of the repair process
Research baseLarge preclinical literature, limited human dataPreclinical, with very little human dataNot yet studied as a combination
StatusNot FDA-approved; compounded on prescriptionNot FDA-approved; compounded on prescriptionNot FDA-approved; compounded on prescription
Tested sportProhibited as a non-approved substanceProhibited as a non-approved substanceProhibited; raise it at your assessment

Prefer to start simple? BPC-157 on its own is the component with the larger research base, and your clinician will help you choose.

Single peptide or stack?

Both are reasonable choices, and the right one depends on your goal. The stack suits people who want both mechanisms covered in one protocol. A single peptide makes it easier to read your own response, because there is only one variable.

Either way, your plan starts with a goal and a review date, so every follow-up has something concrete to measure. What adding TB-500 is meant to do walks through the reasoning behind the pairing.

What the program includes

Every Wolverine Stack prescription at ACT 2 comes with the same clinical structure:

Clinician-led assessment and prescription. A licensed clinician reviews your history, goals and current medications, and prescribes only when it is appropriate for you.

A licensed U.S. compounding pharmacy. Your prescription is prepared individually for you by a licensed U.S. compounding pharmacy.

Baseline labs and monitoring. A Comprehensive Lab Panel before you start, and the relevant markers rechecked as you go.

A published monthly price. What you pay is on the pricing page before you book, with no hidden consult charge.

Follow-up and adjustment. Your clinician reviews progress against the goals you agreed at the start and adjusts the plan, including when to pause or stop.

No membership fee. There is no fee to be assessed, and you pay for treatment only if it is prescribed and you choose to go ahead.

Getting the most from it

Recovery peptides support the work; they do not replace it. Progressive loading, sleep, protein and time are what rebuild tissue, and your plan covers all of them.

An injury that needs a diagnosis gets one first. If imaging or a specialist opinion is the right next step, your clinician will say so.

Two peptides means two sets of unknowns. Long-term human safety data does not exist for either, so your history and medications are reviewed before anything is prescribed, and you are followed up throughout.

How it's delivered

How it works at ACT 2

A compounded preparation, dispensed by a licensed pharmacy on an individual prescription. How it is taken is set by the prescribing clinician after a review. We do not publish dosing information for any medication — that is a clinical decision made for you individually.

Who it's for

Who it's for

Adults over 45 with a specific recovery goal, such as a stubborn strain or a heavy training block, who have the basics of sleep, protein and loading in place and want a clinician-led protocol. Baseline labs come first. If you compete in a drug-tested sport, raise it at your assessment, because both peptides are prohibited under anti-doping rules. See peptide therapy.

How to get started

Book your Wolverine Stack visit. A licensed clinician reviews your history, your recovery goal and whether the stack or a single peptide fits it best.

Labs first. A Comprehensive Lab Panel gives your clinician a baseline and sometimes points to something worth addressing alongside the peptides.

A target and a review date. Agreed before you start, so follow-up is about progress, not guesswork.

Tested athletes. Both substances are prohibited in competitive sport as non-approved substances, so raise it at your assessment before anything is prescribed.

Want an anti-inflammatory component too? The Repair & Recovery Stack adds KPV. The peptide therapy hub explains where these fit; pricing is on the pricing page and licensing on states we serve.

Go deeper

Wolverine Stack, question by question

The specific questions people bring to this treatment, each answered on its own page and reviewed the same way this one is.

Low noise. High signal.

What the research shows

Each peptide has its own preclinical literature and limited human data, long-term safety in people has not been studied for either, and no published trial has yet tested the combination against either component alone. Neither is FDA-approved; both are prepared by a licensed compounding pharmacy under an individual prescription. On regulation: in April 2026 the FDA removed twelve peptide substances, BPC-157 and TB-500 among them, from Category 2 of its interim 503A bulk substances list after the nominations were withdrawn. That was not a safety finding, and it did not by itself authorize compounding. In July 2026 the FDA's Pharmacy Compounding Advisory Committee voted to recommend both for the 503A Bulks List. Committee votes are advisory: formal addition to the list requires notice-and-comment rulemaking, which had not completed as of September 2026. The BPC-157 regulatory page covers both substances.

How we write and review our content

Questions

Frequently asked questions

  • They have not been compared head to head in a published trial. The stack covers two mechanisms; a single peptide is simpler to evaluate. Your clinician will help you choose, and What adding TB-500 is meant to do sets out the reasoning.

  • A synthetic fragment related to thymosin beta-4, studied for a role in tissue repair and blood-vessel formation, largely in preclinical models.

  • No. Neither is FDA-approved for any use. Both are prepared by a licensed compounding pharmacy under an individual prescription.

  • It is a nickname from the peptide community, not a clinical term. We use it because it is what people search for.

  • It is a good question for your assessment. A single peptide is simpler to evaluate, and BPC-157 alone has the larger research base of the two. Some people prefer the stack's two-mechanism approach, and your clinician will help you decide.

  • Neither component has long-term human safety data, so taking two means two sets of unknowns, and it is harder to tell which one is responsible if anything changes. That is why your history and medications are reviewed first and you are followed up throughout.

  • Yes. BPC-157 and TB-500 are both prohibited in competitive sport as non-approved substances. If you are tested, raise it at your assessment before starting.

  • No, and the difference matters. Thymosin beta-4 is a naturally occurring protein that has been through human trials. TB-500 is a short synthetic peptide corresponding to part of it, and it is not the molecule those trials studied.

  • That is what follow-up is for. Your clinician reviews progress against the target you set together and adjusts the plan, whether that means changing course, simplifying to one peptide or stopping.

Own your next chapter

See if Wolverine Stack fits your plan

The right plan begins with knowing where you are. Start with a short eligibility check and a baseline — and we'll tell you, honestly, what fits.

We measure first. Then we act.

ACT 2 Health provides clinician-led care. Treatments described are available only to eligible patients following clinical evaluation and within applicable regulations. This page is educational and is not medical advice. Individual results vary.