
Where to begin
Personalized Weight Loss, Hormone & Peptide Care
Choose the path that fits — or go straight to weight loss. Every plan starts the same way: we measure first.
We measure first
Every plan starts with your labs
A comprehensive blood panel, analyzed in a functional health report that reviews your full results and flags anything that may need follow-up — the baseline every treatment decision is built on. Targeted panels for hormones, gut health, methylation and fertility are added only where your results point.
$199Comprehensive Lab Panel · one-time · functional health report included
- Metabolic & blood sugar
- Hormones & pituitary signals
- Thyroid function
- Heart & inflammation
- Blood count, kidney & liver
- Nutrients, incl. vitamin D & iron
What the Comprehensive Lab Panel covers. Lab testing is not currently available in New York, New Jersey or Rhode Island.
Built around your history
Care shaped by how you've lived
An athletic past or a demanding career changes what is worth measuring. Each has a program of its own.

Your sport left a mark
Some of it protective, some not. Labs read against what your training asked of you, not a reference range in isolation.
Care for athletes
The layer between annual physicals
Full panels, clinician interpretation and repeat measurement — remote, around your calendar, at published prices.
Care for executivesMeasure first
Clarity and control over how you age.
ACT 2 is membership-led care, not one-off services. We measure your biomarkers, build a plan around your body, and adjust over time. No guesswork. No generic advice.
- Online questionnaire
- Clinician-led
- Biomarker-informed
- 100% online
- Confidential
- Transparent pricing
“ACT 2 gave me clarity I never found in clinics, supplements, or wellness apps. If you're tired of generic advice, this is where it starts.”
Question 1 of 5
What brings you to ACT 2?
Your main goal right now.
Leading protocols
Protocols built around your goals.
Clinician-designed treatments — from GLP-1 weight loss to hormone optimization, peptides, and longevity — paired with ongoing medical guidance and progress you can track.
Comprehensive Lab Panel
A comprehensive blood panel establishing your baseline across key health markers.
Semaglutide Injection
CompoundedA GLP-1 receptor agonist that works with your body's appetite and blood-sugar signaling to support weight management.
Tirzepatide Injection
CompoundedA dual GLP-1 and GIP receptor agonist that supports appetite regulation and weight management.
NAD+ Injection
CompoundedA coenzyme central to cellular energy, explored to support energy and recovery in midlife.
Peptide Therapy
Prepare for your 2nd Act
Peptide therapy isn't just for elite athletes or biohackers. It's for anyone who feels like their body isn't keeping up with their life anymore. Most of our patients see themselves in one of these.

Athletes & active adults
Recovery peptides such as BPC-157 and the Wolverine Stack, alongside sermorelin and NAD+, are prescribed under clinical guidance to support recovery and cellular energy. Individual results vary.

Menopause & perimenopause
As hormones shift, targeted therapy is used to address energy, sleep and mood under clinical oversight. Individual results vary.

Busy executives & professionals
High-output lives demand focus and recovery. Peptides like NAD+ are explored under clinical guidance as part of that picture.

Andropause & midlife men
When testosterone and vitality dip, clinician-led hormone therapy addresses energy, drive and strength. Individual results vary.

Weight-loss seekers
Clinician-designed GLP-1 protocols address appetite, metabolism and glucose regulation as part of a monitored plan. Individual results vary, and eligibility is determined by a licensed provider.
Not sure where you fit?
Take the assessment.
A few questions is all it takes to find your protocol.
Get startedHow it works
A clear path, start to finish.
Measure first. Then a plan built around your body — reviewed by a clinician, delivered to your door, and adjusted over time.
Step 1
Start your online assessment
Answer a few questions about your goals and medical history.
Step 2
Meet your clinician
A licensed medical professional reviews your case — fully online, on your schedule.
Step 3
Get your personalized plan
Your clinician tailors a protocol to your biomarkers and goals.
Step 4
Treatment delivered
Your prescription ships to your door, with ongoing support and adjustments.
Physician-led
Care with a name and a face
Your plan is built and overseen by licensed physicians — not an algorithm. Meet the clinicians leading longevity, metabolic, and women's health at ACT 2.

Benjamin H. Krasne, M.D.
Practice focus: Longevity & Metabolic Health
M.D. · Board-Certified in Anesthesiology (American Board of Anesthesiology)
View profile
Johnathan Chance Miller, M.D.
Holistic & Longevity Medicine
M.D. · Holistic & Integrative Medicine
View profile
Vanessa Niles, R.N., M.D., F.A.C.O.G.
Women's Health · Obstetrics & Gynecology
M.D., R.N. · Board-Certified OB-GYN, FACOG
View profileJason M. Hechtman, M.D.
Men's Health · Testosterone & Longevity
M.D. · Board-Certified by the American Board of Surgery
View profileJames Reichman, M.D.
Urology · Men's Sexual Health
M.D. · Board-Certified Urologist
View profileKimberlee A. Coleman, M.D.
Women's Health · Obstetrics & Gynecology
M.D. · Board-Certified OB-GYN (American Board of Obstetrics & Gynecology)
View profileZaman Javaheri, M.D.
Longevity · Weight Loss & Diagnostics
M.D. · Nuclear Medicine & Family Medicine
View profileAmanda Malamud, MSPAS, MPH, PA-C
Internal Medicine · Weight Loss & Longevity
MSPAS, MPH, PA-C · Certified Physician Assistant
View profileYour second act starts now
Ready to feel like yourself again?
Take a quick online questionnaire and get a clinician-guided plan built around your body. No guesswork — just a clear path forward.
From the journal
Insights for your second act.
September 16, 2026 · 5 min read
Who Should Not Take PT-141
Cardiovascular disease and uncontrolled blood pressure are the clear exclusions. The larger group is people for whom something else would work better.
Read moreSeptember 16, 2026 · 5 min read
PT-141 and Other Medications
Blood pressure medication is the main consideration, and slowed stomach emptying affects anything taken by mouth around the same time.
Read moreSeptember 16, 2026 · 5 min read
B12 and Other Medications
Several common medications lower B12 over years, and one anesthetic inactivates it outright. What to disclose, and the folate trap worth knowing about.
Read more- ACT 2 is a premium, clinician-led membership for adults in their second act. We focus on metabolic health, hormone optimization, and peptide therapy — measuring your biomarkers first, then building a plan around your body and adjusting it over time.
- Four steps: start a short online assessment, have a licensed clinician review your case, receive a personalized plan built around your biomarkers, and get your treatment delivered to your door with ongoing support. It's membership-led care, not one-off services.
- Adults — both men and women — in their 40s, 50s, and beyond who want measurable, clinician-guided support for energy, weight, hormones, recovery, and healthy aging.
- Eligibility is determined by a clinician based on your assessment and health history. The quickest way to find out is to see if you're eligible — there's no obligation.
- Yes. Assessment, clinician review, and ongoing support are fully online, and prescriptions ship to your door.


