Best Men's Hormone Clinics (2026)
ACT 2 Health publishes this guide and ranks itself first. The criteria we used are below, and every other entry links to that provider's own site so you can check the details yourself.
Six US men's hormone and TRT providers compared on labs before prescribing, live visits, published prices and where they treat. Checked September 2026.
ACT 2 Health Clinical Team ยท Updated September 24, 2026
Medically reviewed by Benjamin H. Krasne, M.D.
Most men who look for a hormone clinic are not looking for a product. They want to know whether low testosterone is actually the explanation for how they feel, and if it is, who will treat it carefully. The answer starts with measurement. This guide compares six US options, online and in person, on whether they measure before prescribing, how you meet the clinician, what they publish about price, and where they can treat you.
How we chose
Each provider below was operating and offering men's hormone care in September 2026, and every fact about it comes from its own website, linked in each entry. We compared them on five criteria:
- Labs before prescribing. Does the provider require bloodwork before testosterone is prescribed?
- Live clinician involvement. Is there a live visit (video, phone or in person) with a prescribing clinician?
- Ongoing monitoring. Does the provider describe follow-up labs after treatment starts?
- Published pricing. Can you see what it costs, and what is included, before signing up?
- Stated coverage and credentials. Does the provider say where it treats and who leads care?
We did not rank on reviews, before-and-after photos or outcome claims, and we did not repeat any provider's results statistics.
The list
1. ACT 2 Health
Best for: men over 45 who want testosterone measured and discussed before anything is prescribed, with every price published.
ACT 2 Health is a 100% online telemedicine platform with no physical clinic, available for clinical care in all 50 states. For testosterone specifically, bloodwork and a live visit with a clinician are both required before a prescription, and there is no add-to-cart route. Labs are drawn at a local patient service center, with results usually back within days. After starting, the plan includes follow-ups and repeat labs, and it is adjusted over time.
Prices are published in full on the pricing page: TRT from $249 for the first month, then $149/month; the Comprehensive Lab Panel is $199 one-time. For men who want to discuss a non-testosterone route, an Enclomiphene/DHEA/Boron/Pregnenolone ODT is $129/month; it is compounded, and compounded medications are not FDA-approved and are not reviewed by the FDA for safety or effectiveness. There is no membership fee, and the eligibility check is free. Physicians are named with license and NPI numbers on the doctors page. More on the approach is on the men's health page and in the testosterone guide.
Worth knowing: lab testing is not available in New York, New Jersey or Rhode Island; men there can still be seen and can upload recent bloodwork from their own physician.
Not the right fit if: you want an in-person physical exam or clinic visits, you need insurance billing, you want testosterone without a live visit, or you are in NY, NJ or RI and need labs ordered for you.
2. Marek Health
Best for: men who want extensive lab work and a coach alongside the prescriber.
Marek Health describes itself as a platform that connects clients with partnered medical providers, and says plainly that it "is not a healthcare clinic" (Marek FAQ). Care starts with a video intake with a health coach, then comprehensive lab work that must be completed before the first provider consultation. Marek lists follow-up labs 6 to 12 weeks after starting treatment, then every six months, with provider visits every six months. It also requires a copy of an annual in-person physical.
Worth knowing: we did not find package prices on the pages we checked. Marek says its program is available in all 50 states but that specific treatments may be limited by state, and it does not work with insurance.
Not the right fit if: you do not have, and do not want to arrange, an annual physical, or you want to see prices before you start.
3. Defy Medical
Best for: men who want a long-running TRT practice with a physical clinic as a backstop.
Defy Medical says it has offered testosterone therapy by telemedicine for more than a decade, led by medical director Dr. Justin Saya (Defy). It requires comprehensive lab work and an up-to-date physical exam for any hormone protocol (Defy). Defy's FAQ says the average cost of TRT for a male patient is under $175 per month for the first year, including testosterone, an aromatase inhibitor, lab work and consultations, dropping to around $125 per month after that (Defy).
Worth knowing: those figures are averages, not a fixed price. Defy treats patients by telemedicine in "most states" and does not list which ones on the pages we checked; it also runs an in-person clinic in Tampa, Florida (Defy).
Not the right fit if: you want a fixed, itemized monthly price up front.
4. Hone Health
Best for: men who want frequent testing bundled into a membership.
Hone starts with a $65 biomarker test, taken at home or at a lab, followed by a telehealth consult with a Hone-affiliated licensed physician who reviews the results (Hone). The Premium membership is listed at $155/month plus medication, with testing every three months; Basic is $25/month with testing every six months (Hone). Hone says its affiliated medical practices are independently owned and operated by licensed physicians.
Worth knowing: Hone's men's memberships are offered only in select states, and the list differs by membership type; Premium requires at-lab testing (Hone).
Not the right fit if: you live in a state Hone does not serve, or you want medication cost included in one monthly figure.
5. Maximus
Best for: men who want several testosterone routes to choose from, fully online.
Maximus offers enclomiphene, testosterone cream, oral testosterone and injectable testosterone, and says evaluation involves a health questionnaire and an at-home lab test reviewed by a Maximus doctor (Maximus). It lists protocols from $99.99/month, with combination protocols from $149.99 to $199.99/month, and says consultations and ongoing monitoring are included. Its site states that compounded medications are not FDA-approved.
Worth knowing: Maximus lab testing is available in 47 states and not in Rhode Island, New York or New Jersey (Maximus). Its testosterone page presents results figures from its own observational studies; we did not use them here.
Not the right fit if: you are in RI, NY or NJ, or you prefer a clinic draw and an in-person exam.
6. Gameday Men's Health
Best for: men who want to walk in and have testosterone checked the same day.
Gameday says it has 400+ clinics across the US and Canada, offers a free testosterone test, and can run on-site testosterone and PSA screening with results in as little as 15 minutes (Gameday). Most initial visits and labs are completed in person. Its TRT page lists testosterone cypionate injections, testosterone pellets and clomid/enclomiphene at $199/mo (Gameday).
Worth knowing: clinics are independently owned and operated, so the clinician, services and experience vary by location.
Not the right fit if: there is no clinic near you, or you want a fully online relationship.
Comparison table
| Provider | Format | Physician-led? | Labs before prescribing? | Published pricing? | Where available |
|---|---|---|---|---|---|
| ACT 2 Health | Online | Yes, named physicians with license and NPI | Yes, plus a live visit, for testosterone | Yes, full price list | All 50 states (labs not in NY, NJ, RI) |
| Marek Health | Online platform with partnered providers | Partnered physicians and providers | Yes, before first consult; annual physical required | Not stated | All 50 states, some treatments limited |
| Defy Medical | Online, plus Tampa clinic | Yes, MD medical director with PAs and NPs | Yes, plus a current physical exam | Average cost stated | "Most states" |
| Hone Health | Online | Hone-affiliated licensed physicians | Yes, at home or at a lab | Yes | Select states |
| Maximus | Online | States board-certified doctors | Yes, at-home lab test | Yes | Labs in 47 states (not RI, NY, NJ) |
| Gameday Men's Health | In-person | Clinic providers; independently owned clinics | Yes, most in person | Yes, on TRT page | 400+ clinics, US and Canada |
Questions to ask any men's hormone clinic
The providers above differ more in process than in the medications they offer. These questions bring the differences out quickly, and a good clinic answers them without hesitation:
- What will you measure before prescribing, and who reviews it? Ask which markers are included and whether the prescriber, not only a coach or an algorithm, reviews them.
- Will I speak with the prescriber live? Some services are built around a live visit and some around messaging. Know which you are signing up for.
- How often are labs repeated once I start, and are they in the price? Follow-up bloodwork is how a clinician checks how you are responding, so find out whether follow-up bloodwork is included or billed separately.
- Is this medication FDA-approved or compounded? If it is compounded, ask whether it is prepared by a 503A pharmacy or a 503B outsourcing facility. Compounded medications are not FDA-approved and are not reviewed by the FDA for safety or effectiveness.
- What happens if the telemedicine rules change? Testosterone is a controlled substance, and the current DEA telemedicine extension runs through December 31, 2026 (Federal Register). Ask how the provider would handle an in-person requirement if one returns.
- Who do I contact between visits? Side effects and questions do not wait for the next scheduled appointment.
Before you choose
Testosterone therapy is a long-term decision, and it is not right for every man; our page on who should not take TRT covers the common reasons. If fertility matters to you, read TRT vs enclomiphene and raise it on your first visit. Whichever provider you choose, confirm three things: that testosterone is measured before prescribing, that a named, licensed clinician is responsible for your care, and that follow-up labs are part of the plan rather than an optional extra.
Individual results vary. Eligibility is determined by a licensed provider.
Sources
- https://www.federalregister.gov/documents/2025/12/31/2025-24123/fourth-temporary-extension-of-covid-19-telemedicine-flexibilities-for-prescription-of-controlled
- https://marekhealth.com/faqs
- https://marekhealth.com
- https://www.defymedical.com/services/trt/
- https://www.defymedical.com/faq/how-much-does-trt-cost-with-defy-medical/
- https://www.defymedical.com/tampa-clinic/
- https://www.defymedical.com/about-us/
- https://honehealth.com/how-it-works/
- https://honehealth.com
- https://help.honehealth.com/hc/en-us/articles/40162108823319-Hone-Health-Service-Availability-by-State-2026
- https://www.maximustribe.com/testosterone
- https://www.maximustribe.com/labs
- https://gamedaymenshealth.com
- https://gamedaymenshealth.com/service/testosterone-replacement-therapy
Frequently asked questions
You should expect to. Every provider in this guide describes bloodwork as part of qualifying for testosterone therapy, whether at a lab, at home or in a clinic. At ACT 2 Health, bloodwork and a live visit with a clinician are both required before testosterone is prescribed. Be cautious of any service willing to prescribe testosterone without measuring it first.
It can be. Testosterone is a controlled substance, and a temporary DEA extension allows it to be prescribed by telemedicine without a prior in-person visit through December 31, 2026, when conditions are met. What separates careful services from the rest is whether they measure before prescribing, who reviews your results, and whether follow-up labs are built in. Check that the prescriber is named and licensed, and ask how monitoring works.
Listed figures among the providers here, as of September 2026, ran from $99.99/month for some Maximus protocols to $249 for an ACT 2 Health first month. Some providers add memberships, labs or visit fees on top, and some include them in the monthly price. Compare what is included, not just the headline price.
Testosterone therapy supplies testosterone directly. Enclomiphene works differently, by prompting the body's own signaling. Several providers offer both. At ACT 2 Health, enclomiphene is part of a compounded preparation, and compounded medications are not FDA-approved and are not reviewed by the FDA for safety or effectiveness. A clinician can explain which fits your labs and goals.
Testosterone therapy is not appropriate for everyone. Certain health conditions, fertility plans and lab findings can make it the wrong choice, which is why a clinician reviews your history and bloodwork first. Our page on who should not take TRT walks through the common reasons, and your clinician will go through your specific situation.
This page is educational and is not medical advice. Treatments are available only to eligible patients following clinical evaluation. How we write and review our content.