DSIP
A sleep peptide whose name promises considerably more than its evidence delivers.
- Explored for sleep quality, where the human evidence is weakest of the peptides offered here
- Considered only after the common and treatable causes of poor sleep have been excluded
Explored, not established. The name describes what was seen in an animal model fifty years ago, not a demonstrated effect in people.
Pricing confirmed after eligibility · prescription treatment
What DSIP is
DSIP, delta sleep-inducing peptide, is a short peptide named for an effect observed in rabbits in the 1970s. It has been studied since for a role in sleep and in stress response, in a small and largely inconclusive human literature. It is prepared by a licensed compounding pharmacy under a prescription written for you and is not FDA-approved.
How it works here
Every plan follows one path. Each step feeds the next. See the Peptide Therapy approach.
- 01
Measure
We baseline your labs, history, and goals.
- 02
Plan
A clinician decides whether this fits — and what else might serve you.
- 03
Act
If appropriate, you start with clear guidance and high-touch support.
- 04
Track
We monitor how you respond on a defined cadence.
- 05
Adjust
Protocols are refined over time. Guided care, not a kit in the mail.
Delivery
A compounded preparation, dispensed by a licensed pharmacy on an individual prescription. How it is taken is set by the prescribing clinician after a review.
Is it right for you?
Adults over 45 whose sleep has been properly assessed — including screening for sleep-disordered breathing, which is far more common and genuinely treatable — and who understand this is the thinnest evidence base on this page. See sleep that does not restore you first.
Often considered alongside
Sermorelin ODT
CompoundedThe needle-free route to sermorelin — offered honestly, including what we can't tell you about it.
View treatmentComprehensive Lab Panel
A comprehensive blood panel establishing your baseline across key health markers.
View treatmentProducts marked Compounded are prepared by a licensed compounding pharmacy under a prescription written for you. Compounded medications are not FDA-approved and are not equivalent to or interchangeable with any branded product.
An honest word on the evidence
Of everything offered here, DSIP has the weakest case, and it would be dishonest to present it otherwise. The peptide is named for a rabbit study; the human sleep research that followed is small, old and mixed. It is also the one peptide of the seven considered by the FDA's Pharmacy Compounding Advisory Committee in July 2026 that the committee voted against recommending for the 503A Bulks List. These peptides sit in an unsettled regulatory position. In April 2026 the FDA removed twelve peptide substances from Category 2 of its interim 503A bulk substances list, this one among them — a step that followed the nominators withdrawing their nominations rather than any safety finding, and one that does not by itself authorize compounding. In July 2026 the Pharmacy Compounding Advisory Committee voted on whether seven of them should be added to the 503A Bulks List. That vote is a recommendation, not a decision: formal addition requires notice-and-comment rulemaking, which has not completed. Nothing here is FDA-approved for any use. If you are here because you sleep badly, the useful first step is finding out why — not this.
Frequently asked questions
That is not established in people. The name comes from an animal experiment, and the human work since has been small and inconclusive. See what the sleep evidence shows.
In July 2026 it voted against recommending DSIP, listed as emideltide, for the 503A Bulks List — the only one of the seven peptides considered that it declined. See the regulatory position.
No. Sleep-disordered breathing is common, frequently missed, and treatable. Screening comes first.
No, and unlike the other peptides here it does not currently have a favorable advisory recommendation behind it either.
See if DSIP fits your plan
The right plan begins with knowing where you are. Start with a short eligibility check and a baseline — and we'll tell you, honestly, what fits.
We measure first. Then we act.
ACT 2 Health provides clinician-led care. Treatments described are available only to eligible patients following clinical evaluation and within applicable regulations. This page is educational and is not medical advice. Individual results vary.